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FOXO4 Inhibits the Migration and Metastasis of Colorectal Cancer by Regulating the APC2/β-Catenin Axis

Objective: Adenomatous polyposis coli 2 (APC2) is a colorectal cancer (CRC) tumor-suppressor gene. The progression of several kinds of cancer is closely associated with Forkhead box O4 (FOXO4). However, the function of FOXO4 in CRC is unclear. This study focused on the role of FOXO4 and the relation...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Wang, Lin, Xu, Xuehu, Han, Puqing, Wu, Jinghao, Tian, Xuan, Li, Mingsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495124/
https://www.ncbi.nlm.nih.gov/pubmed/34631691
http://dx.doi.org/10.3389/fcell.2021.659731