Dapagliflozin Mediates Plin5/PPARα Signaling Axis to Attenuate Cardiac Hypertrophy

Objective: The purpose of this study was to investigate the effect of dapagliflozin (DAPA), a sodium-glucose cotransporter 2 inhibitor, on relieving cardiac hypertrophy and its potential molecular mechanism. Methods: Cardiac hypertrophy induced by abdominal aortic constriction (AAC) in mice, dapagli...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Jing, Zhao, Huanhuan, Qi, Xin, Wei, Liping, Li, Zihao, Li, Chunpeng, Zhang, Xiaoying, Wu, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495133/
https://www.ncbi.nlm.nih.gov/pubmed/34630108
http://dx.doi.org/10.3389/fphar.2021.730623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495133/
https://www.ncbi.nlm.nih.gov/pubmed/34630108
http://dx.doi.org/10.3389/fphar.2021.730623

Ejemplares similares