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Dapagliflozin Mediates Plin5/PPARα Signaling Axis to Attenuate Cardiac Hypertrophy
Objective: The purpose of this study was to investigate the effect of dapagliflozin (DAPA), a sodium-glucose cotransporter 2 inhibitor, on relieving cardiac hypertrophy and its potential molecular mechanism. Methods: Cardiac hypertrophy induced by abdominal aortic constriction (AAC) in mice, dapagli...
Autores principales: | Yu, Jing, Zhao, Huanhuan, Qi, Xin, Wei, Liping, Li, Zihao, Li, Chunpeng, Zhang, Xiaoying, Wu, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495133/ https://www.ncbi.nlm.nih.gov/pubmed/34630108 http://dx.doi.org/10.3389/fphar.2021.730623 |
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