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Evaluation of [(18)F]PI-2620, a second-generation selective tau tracer, for assessing four-repeat tauopathies

Tau aggregates represent a key pathologic feature of Alzheimer’s disease and other neurodegenerative diseases. Recently, PET probes have been developed for in vivo detection of tau accumulation; however, they are limited because of off-target binding and a reduced ability to detect tau in non-Alzhei...

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Detalles Bibliográficos
Autores principales: Tezuka, Toshiki, Takahata, Keisuke, Seki, Morinobu, Tabuchi, Hajime, Momota, Yuki, Shiraiwa, Mika, Suzuki, Natsumi, Morimoto, Ayaka, Nakahara, Tadaki, Iwabuchi, Yu, Miura, Eisuke, Yamamoto, Yasuharu, Sano, Yasunori, Funaki, Kei, Yamagata, Bun, Ueda, Ryo, Yoshizaki, Takahito, Mashima, Kyoko, Shibata, Mamoru, Oyama, Munenori, Okada, Kensuke, Kubota, Masahito, Okita, Hajime, Takao, Masaki, Jinzaki, Masahiro, Nakahara, Jin, Mimura, Masaru, Ito, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495135/
https://www.ncbi.nlm.nih.gov/pubmed/34632382
http://dx.doi.org/10.1093/braincomms/fcab190