Ethyl 2-[2,3,4-Trimethoxy-6-(1-Octanoyl)Phenyl] Acetate (TMPA) Ameliorates Lipid Accumulation by Disturbing the Combination of LKB1 with Nur77 and Activating the AMPK Pathway in HepG2 Cells and Mice Primary Hepatocytes

BACKGROUND: The AMP-activated protein kinase alpha (AMPKα) pathway has widely been considered a key factor in energy metabolism. Ethyl 2-[2,3,4-trimethoxy-6-(1-octanoyl)phenyl] acetate (TMPA) is a novel AMPK agonist, which influences the stability of Nuclear Receptor Subfamily 4, Group A, Member 1 (...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoyu, Li, Guangbing, Guo, Changfa, Zhang, Jiayao, Kong, Junjie, He, Jingyi, Li, Feiyu, Liu, Yong, Yang, Yang, Lu, Ziwen, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495146/
https://www.ncbi.nlm.nih.gov/pubmed/34629883
http://dx.doi.org/10.2147/DMSO.S321246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495146/
https://www.ncbi.nlm.nih.gov/pubmed/34629883
http://dx.doi.org/10.2147/DMSO.S321246

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