USP47-Mediated Deubiquitination and Stabilization of TCEA3 Attenuates Pyroptosis and Apoptosis of Colorectal Cancer Cells Induced by Chemotherapeutic Doxorubicin

The ubiquitin–proteasome system regulates a variety of cellular processes including growth, differentiation and apoptosis. While E1, E2, and E3 are responsible for the conjugation of ubiquitin to substrates, deubiquitinating enzymes (DUBs) reverse the process to remove ubiquitin and edit ubiquitin c...

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Detalles Bibliográficos
Autores principales: Hou, Xiaodan, Xia, Jun, Feng, Yuan, Cui, Long, Yang, Yili, Yang, Peng, Xu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495243/
https://www.ncbi.nlm.nih.gov/pubmed/34630087
http://dx.doi.org/10.3389/fphar.2021.713322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495243/
https://www.ncbi.nlm.nih.gov/pubmed/34630087
http://dx.doi.org/10.3389/fphar.2021.713322

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