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A Bumpy Ride of Mycobacterial Phagosome Maturation: Roleplay of Coronin1 Through Cofilin1 and cAMP

Phagosome-lysosome fusion in innate immune cells like macrophages and neutrophils marshal an essential role in eliminating intracellular microorganisms. In microbe-challenged macrophages, phagosome-lysosome fusion occurs 4 to 6 h after the phagocytic uptake of the microbe. However, live pathogenic m...

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Detalles Bibliográficos
Autores principales: Saha, Saradindu, Hazra, Arnab, Ghatak, Debika, Singh, Ajay Vir, Roy, Sadhana, BoseDasgupta, Somdeb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495260/
https://www.ncbi.nlm.nih.gov/pubmed/34630380
http://dx.doi.org/10.3389/fimmu.2021.687044