Treatment resistance analysis reveals GLUT‐1‐mediated glucose uptake as a major target of synthetic rocaglates in cancer cells

Rocaglates are natural compounds that have been extensively studied for their ability to inhibit translation initiation. Rocaglates represent promising drug candidates for tumor treatment due to their growth‐inhibitory effects on neoplastic cells. In contrast to natural rocaglates, synthetic analogu...

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Detalles Bibliográficos
Autores principales: Sieber‐Frank, Julia, Stark, Hans‐Jürgen, Kalteis, Simon, Prigge, Elena‐Sophie, Köhler, Richard, Andresen, Carolin, Henkel, Thomas, Casari, Georg, Schubert, Tobias, Fischl, Wolfgang, Li‐Weber, Min, Krammer, Peter H., von Knebel Doeberitz, Magnus, Kopitz, Jürgen, Kloor, Matthias, Ahadova, Aysel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495295/
https://www.ncbi.nlm.nih.gov/pubmed/34546000
http://dx.doi.org/10.1002/cam4.4212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495295/
https://www.ncbi.nlm.nih.gov/pubmed/34546000
http://dx.doi.org/10.1002/cam4.4212

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