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Development of mesothelin-specific CAR NK-92 cells for the treatment of gastric cancer

Background: The application of chimeric antigen receptor (CAR) NK cells in solid tumors is hindered by lack of tumor-specific targets and inefficient CAR NK cell efficacy. It has been reported that mesothelin (MSLN) may be an ideal immunotherapy target for gastric cancer. However, the feasibility of...

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Detalles Bibliográficos
Autores principales: Cao, Bihui, Liu, Manting, Huang, Jingjun, Zhou, Jingwen, Li, Junping, Lian, Hui, Huang, Wensou, Guo, Yongjian, Yang, Shuo, Lin, Liteng, Cai, Mingyue, Zhi, Cheng, Wu, Jingqiang, Liang, Licong, Hu, Yuling, Hu, Hong, He, Jinping, Liang, Baoxia, Zhao, Qi, Zhu, Kangshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495380/
https://www.ncbi.nlm.nih.gov/pubmed/34671203
http://dx.doi.org/10.7150/ijbs.64630