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Single-cell RNA sequencing reveals spatiotemporal heterogeneity and malignant progression in pancreatic neuroendocrine tumor

Aims: Using Single-cell RNA sequencing (scRNA-seq), we explored the spatiotemporal heterogeneity of pancreatic neuroendocrine tumors (pNETs) and the underlying mechanism for malignant progression. Methods: scRNA-seq was conducted on three tumor tissues (two primary tissues from different sites, one...

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Detalles Bibliográficos
Autores principales: Zhou, Yu, Liu, Siyang, Liu, Chao, Yang, Jiabin, Lin, Qing, Zheng, Shangyou, Chen, Changhao, Zhou, Quanbo, Chen, Rufu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495381/
https://www.ncbi.nlm.nih.gov/pubmed/34671197
http://dx.doi.org/10.7150/ijbs.61717