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Long non-coding RNA MEG3 promotes cisplatin-induced nephrotoxicity through regulating AKT/TSC/mTOR-mediated autophagy

Cis-Diamminedichloroplatinum (II) (DDP)-induced nephrotoxicity (DDPIN) may cause irreversible renal injury associated with high morbidity and mortality. Current standard therapies have not achieved satisfactory clinical outcomes due to unclear molecular and cellular mechanisms. Therefore, exploring...

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Detalles Bibliográficos
Autores principales: Jing, Xu, Han, Jinming, Zhang, Junhao, Chen, Yi, Yuan, Juan, Wang, Jue, Neo, Shiyong, Li, Shuijie, Yu, Xueyuan, Wu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495387/
https://www.ncbi.nlm.nih.gov/pubmed/34671212
http://dx.doi.org/10.7150/ijbs.58910