Suppression of neuronal cholesterol biosynthesis impairs brain functions through insulin-like growth factor I-Akt signaling

Some relationship between abnormal cholesterol content and impairment of insulin/insulin-like growth factor I (IGF-1) signaling has been reported in the pathogenesis of Alzheimer's disease (AD). However, the underlying mechanism of this correlation remains unclear. It is known that 3-β hydroxyc...

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Detalles Bibliográficos
Autores principales: Liu, Ting, Li, Yang, Yang, Baoyu, Wang, Haozhen, Lu, Chen, Chang, Alan K, Huang, Xiuting, Zhang, Xiujin, Lu, Ziyin, Lu, Xiuli, Gao, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495388/
https://www.ncbi.nlm.nih.gov/pubmed/34671194
http://dx.doi.org/10.7150/ijbs.63512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495388/
https://www.ncbi.nlm.nih.gov/pubmed/34671194
http://dx.doi.org/10.7150/ijbs.63512

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