Lrp6 Genotype affects Individual Susceptibility to Nonalcoholic Fatty Liver Disease and Silibinin Therapeutic Response via Wnt/β-catenin-Cyp2e1 Signaling

Background: Nonalcoholic fatty liver disease (NAFLD) is a serious threat to human health worldwide, with a high genetic susceptibility. Rs2302685, a functional germline variant of LRP6, has been recently found to associate with NAFLD risk. This study was aimed to clarify the underlying mechanism ass...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Li-Jie, Lin, Xiu-Xian, Guo, Jing, Xu, Ying, Zhang, Song-Xia, Chen, Dan, Zhao, Qing, Xiao, Jian, Lian, Guang-Hui, Peng, Shi-Fang, Guo, Dong, Yang, Hong, Shu, Yan, Zhou, Hong-Hao, Zhang, Wei, Chen, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495406/
https://www.ncbi.nlm.nih.gov/pubmed/34671210
http://dx.doi.org/10.7150/ijbs.63732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495406/
https://www.ncbi.nlm.nih.gov/pubmed/34671210
http://dx.doi.org/10.7150/ijbs.63732

Ejemplares similares