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Endocervical Regulatory T Cells Are Associated With Decreased Genital Inflammation and Lower HIV Target Cell Abundance

Regulatory T cells (Tregs) play important roles in tissue homeostasis, but few studies have investigated tissue Tregs in the context of genital inflammation, HIV target cell density, and vaginal microbiota in humans. In women from Nairobi (n=64), the proportion of CD4+ CD25+ CD127(low) Tregs in the...

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Detalles Bibliográficos
Autores principales: Ssemaganda, Aloysious, Cholette, Francois, Perner, Michelle, Kambaran, Cheli, Adhiambo, Wendy, Wambugu, Peter M., Gebrebrhan, Henok, Lee, Amy, Nuhu, Faisal, Mwatelah, Ruth S., Jahan, Naima, Omole, Tosin E., Wanjiru, Tabitha, Gitau, Apollo, Kimani, Joshua, McKinnon, Lyle R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495419/
https://www.ncbi.nlm.nih.gov/pubmed/34630402
http://dx.doi.org/10.3389/fimmu.2021.726472