Inhibitory Effects of Rhaponticin on Osteoclast Formation and Resorption by Targeting RANKL-Induced NFATc1 and ROS Activity

The extravagant osteoclast formation and resorption is the main cause of osteoporosis. Inhibiting the hyperactive osteoclastic resorption is considered as an efficient treatment for osteoporosis. Rhaponticin (RH) is a small molecule that has been reported to possess anti-inflammatory, anti-allergic,...

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Detalles Bibliográficos
Autores principales: He, Jianbo, Chen, Kai, Deng, Tiancheng, Xie, Jiewei, Zhong, Kunjing, Yuan, Jinbo, Wang, Ziyi, Xiao, Zhifeng, Gu, Ronghe, Chen, Delong, Li, Xiaojuan, Lin, Dingkun, Xu, Jiake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495440/
https://www.ncbi.nlm.nih.gov/pubmed/34630071
http://dx.doi.org/10.3389/fphar.2021.645140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495440/
https://www.ncbi.nlm.nih.gov/pubmed/34630071
http://dx.doi.org/10.3389/fphar.2021.645140

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