Inhibition of the NLRP3 inflammasome improves lifespan in animal murine model of Hutchinson–Gilford Progeria

Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson–Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the NLRP3 inflammasome pathway in HGPS skin fibroblasts, an outcome that was associated with morpho...

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Detalles Bibliográficos
Autores principales: González‐Dominguez, Alvaro, Montañez, Raúl, Castejón‐Vega, Beatriz, Nuñez‐Vasco, Jéssica, Lendines‐Cordero, Débora, Wang, Chun, Mbalaviele, Gabriel, Navarro‐Pando, José M, Alcocer‐Gómez, Elísabet, Cordero, Mario D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495449/
https://www.ncbi.nlm.nih.gov/pubmed/34448355
http://dx.doi.org/10.15252/emmm.202114012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495449/
https://www.ncbi.nlm.nih.gov/pubmed/34448355
http://dx.doi.org/10.15252/emmm.202114012

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