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Metformin attenuates H(2)O(2)-induced osteoblast apoptosis by regulating SIRT3 via the PI3K/AKT pathway

Osteoporosis is a common metabolic disease that has a high incidence in postmenopausal women. Studies have indicated that oxidative damage plays an important role in the development of postmenopausal osteoporosis. Metformin has been showed to have the ability to relieve excessive oxidation. The aim...

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Detalles Bibliográficos
Autores principales: Yang, Keda, Pei, Lei, Zhou, Siming, Tao, Lin, Zhu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495548/
https://www.ncbi.nlm.nih.gov/pubmed/34630670
http://dx.doi.org/10.3892/etm.2021.10751