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An enriched environment delays the progression from mild cognitive impairment to Alzheimer's disease in senescence-accelerated mouse prone 8 mice

A previous study demonstrated that middle-aged (5-6 months of age) senescence-accelerated mouse prone 8 (SAMP8) mice can be used as animal models of mild cognitive impairment (MCI). An enriched environment (EE) can mitigate cognitive decline and decrease the pathological changes associated with vari...

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Detalles Bibliográficos
Autores principales: Li, Jian-Zhong, Hao, Xing-Hua, Wu, Hai-Ping, Li, Ming, Liu, Xue-Min, Wu, Zhi-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495563/
https://www.ncbi.nlm.nih.gov/pubmed/34630674
http://dx.doi.org/10.3892/etm.2021.10755