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Suppression of collagen IV alpha‐2 subunit by prolyl hydroxylase domain inhibition via hypoxia‐inducible factor‐1 in chronic kidney disease

Elevation of hypoxia‐inducible factor 1 protein has been shown to be protective in acute kidney injury and HIF1α enhancing drug therapies are currently in clinical trials for the treatment of anemia of chronic kidney disease. Despite its benefits, long‐term HIF1 elevation seems to be associated with...

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Detalles Bibliográficos
Autores principales: Sanaei‐Ardekani, Mohammad, Kamal, Shyreen, Handy, Whitney, Alam, Sidrah, Salaheldin, Aya, Moore, Anderson, Movafagh, Shahrzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495681/
https://www.ncbi.nlm.nih.gov/pubmed/34617686
http://dx.doi.org/10.1002/prp2.872