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Suppression of collagen IV alpha‐2 subunit by prolyl hydroxylase domain inhibition via hypoxia‐inducible factor‐1 in chronic kidney disease
Elevation of hypoxia‐inducible factor 1 protein has been shown to be protective in acute kidney injury and HIF1α enhancing drug therapies are currently in clinical trials for the treatment of anemia of chronic kidney disease. Despite its benefits, long‐term HIF1 elevation seems to be associated with...
Autores principales: | Sanaei‐Ardekani, Mohammad, Kamal, Shyreen, Handy, Whitney, Alam, Sidrah, Salaheldin, Aya, Moore, Anderson, Movafagh, Shahrzad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495681/ https://www.ncbi.nlm.nih.gov/pubmed/34617686 http://dx.doi.org/10.1002/prp2.872 |
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