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1,4-Naphthoquinone Is a Potent Inhibitor of IRAK1 Kinases and the Production of Inflammatory Cytokines in THP-1 Differentiated Macrophages

[Image: see text] Quinones are a class of cyclic organic compounds that are widely distributed in nature and have been shown to exhibit anti-inflammatory, antioxidant, and anticancerous activities. However, the molecular mechanisms/signaling by which these molecules exert their effect are still not...

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Detalles Bibliográficos
Autores principales: Mahmoud, Ismail Sami, Hatmal, Ma’mon M., Abuarqoub, Duaa, Esawi, Ezaldeen, Zalloum, Hiba, Wehaibi, Suha, Nsairat, Hamdi, Alshaer, Walhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495692/
https://www.ncbi.nlm.nih.gov/pubmed/34632188
http://dx.doi.org/10.1021/acsomega.1c03081