Bilateral atypical femoral fractures during denosumab therapy in a patient with adult-onset hypophosphatasia

SUMMARY: Hypophosphatasia (HPP) is a rare and under-recognised genetic defect in bone mineralisation. Patients presenting with fragility fractures may be mistakenly diagnosed as having osteoporosis and prescribed antiresorptive therapy, a treatment which may increase fracture risk. Adult-onset HPPhy...

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Detalles Bibliográficos
Autores principales: Warren, Annabelle M, Ebeling, Peter R, Grill, Vivian, Seeman, Ego, Sztal-Mazer, Shoshana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2021
Materias:
Unique/Unexpected Symptoms or Presentations of a Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495717/
https://www.ncbi.nlm.nih.gov/pubmed/34515659
http://dx.doi.org/10.1530/EDM-21-0096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495717/
https://www.ncbi.nlm.nih.gov/pubmed/34515659
http://dx.doi.org/10.1530/EDM-21-0096

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