A selection-based next generation sequencing approach to develop robust, genotype-specific mutation profiles in Saccharomyces cerevisiae

Distinct mutation signatures arise from environmental exposures and/or from defects in metabolic pathways that promote genome stability. The presence of a particular mutation signature can therefore predict the underlying mechanism of mutagenesis. These insults to the genome often alter dNTP pools,...

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Detalles Bibliográficos
Autores principales: Lamb, Natalie A, Bard, Jonathan E, Buck, Michael J, Surtees, Jennifer A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495734/
https://www.ncbi.nlm.nih.gov/pubmed/33784385
http://dx.doi.org/10.1093/g3journal/jkab099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495734/
https://www.ncbi.nlm.nih.gov/pubmed/33784385
http://dx.doi.org/10.1093/g3journal/jkab099

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