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Transcriptional profiles of genes related to electrophysiological function in Scn5a (+/−) murine hearts
The Scn5a gene encodes the major pore‐forming Na(v)1.5 (α) subunit, of the voltage‐gated Na(+) channel in cardiomyocytes. The key role of Na(v)1.5 in action potential initiation and propagation in both atria and ventricles predisposes organisms lacking Scn5a or carrying Scn5a mutations to cardiac ar...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495800/ https://www.ncbi.nlm.nih.gov/pubmed/34617689 http://dx.doi.org/10.14814/phy2.15043 |