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Transcriptional profiles of genes related to electrophysiological function in Scn5a (+/−) murine hearts

The Scn5a gene encodes the major pore‐forming Na(v)1.5 (α) subunit, of the voltage‐gated Na(+) channel in cardiomyocytes. The key role of Na(v)1.5 in action potential initiation and propagation in both atria and ventricles predisposes organisms lacking Scn5a or carrying Scn5a mutations to cardiac ar...

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Detalles Bibliográficos
Autores principales: Takla, Michael, Edling, Charlotte E., Zhang, Kevin, Saadeh, Khalil, Tse, Gary, Salvage, Samantha C., Huang, Christopher L.‐H., Jeevaratnam, Kamalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495800/
https://www.ncbi.nlm.nih.gov/pubmed/34617689
http://dx.doi.org/10.14814/phy2.15043

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