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Membrane protein regulators of melanoma pulmonary colonization identified using a CRISPRa screen and spontaneous metastasis assay in mice

Metastasis is the spread of cancer cells to a secondary site within the body, and is the leading cause of death for cancer patients. The lung is a common site of metastasis for many cancer types, including melanoma. Identifying the genes involved in aiding metastasis of melanoma cells to the lungs i...

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Detalles Bibliográficos
Autores principales: van der Weyden, Louise, Offord, Victoria, Turner, Gemma, Swiatkowska, Agnes, Speak, Anneliese O, Adams, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495943/
https://www.ncbi.nlm.nih.gov/pubmed/33963380
http://dx.doi.org/10.1093/g3journal/jkab157