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Membrane protein regulators of melanoma pulmonary colonization identified using a CRISPRa screen and spontaneous metastasis assay in mice
Metastasis is the spread of cancer cells to a secondary site within the body, and is the leading cause of death for cancer patients. The lung is a common site of metastasis for many cancer types, including melanoma. Identifying the genes involved in aiding metastasis of melanoma cells to the lungs i...
Autores principales: | van der Weyden, Louise, Offord, Victoria, Turner, Gemma, Swiatkowska, Agnes, Speak, Anneliese O, Adams, David J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495943/ https://www.ncbi.nlm.nih.gov/pubmed/33963380 http://dx.doi.org/10.1093/g3journal/jkab157 |
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