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Self-cleaving ribozymes: substrate specificity and synthetic biology applications

Various self-cleaving ribozymes appearing in nature catalyze the sequence-specific intramolecular cleavage of RNA and can be engineered to catalyze cleavage of appropriate substrates in an intermolecular fashion, thus acting as true catalysts. The mechanisms of the small, self-cleaving ribozymes hav...

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Detalles Bibliográficos
Autores principales: Peng, Huan, Latifi, Brandon, Müller, Sabine, Lupták, Andrej, Chen, Irene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495972/
https://www.ncbi.nlm.nih.gov/pubmed/34704043
http://dx.doi.org/10.1039/d0cb00207k