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HBx facilitates ferroptosis in acute liver failure via EZH2 mediated SLC7A11 suppression

BACKGROUND: Acute liver failure (ALF) is a syndrome of severe hepatocyte injury with high rate of mortality. Hepatitis B virus (HBV) infection is the major cause of ALF worldwide, however, the underlying mechanism by which HBV infection leads to ALF has not been fully disclosed. METHODS: D-GalN-indu...

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Detalles Bibliográficos
Autores principales: Liu, Guo-Zhen, Xu, Xu-Wen, Tao, Shu-Hui, Gao, Ming-Jian, Hou, Zhou-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495979/
https://www.ncbi.nlm.nih.gov/pubmed/34615538
http://dx.doi.org/10.1186/s12929-021-00762-2