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HBx facilitates ferroptosis in acute liver failure via EZH2 mediated SLC7A11 suppression
BACKGROUND: Acute liver failure (ALF) is a syndrome of severe hepatocyte injury with high rate of mortality. Hepatitis B virus (HBV) infection is the major cause of ALF worldwide, however, the underlying mechanism by which HBV infection leads to ALF has not been fully disclosed. METHODS: D-GalN-indu...
Autores principales: | Liu, Guo-Zhen, Xu, Xu-Wen, Tao, Shu-Hui, Gao, Ming-Jian, Hou, Zhou-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8495979/ https://www.ncbi.nlm.nih.gov/pubmed/34615538 http://dx.doi.org/10.1186/s12929-021-00762-2 |
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