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Targeting the RNA demethylase FTO for cancer therapy
N (6)-Methyladenosine (m(6)A) is the most prevalent internal modification on mRNA and represents a new layer of gene expression in eukaryotes. The field of m(6)A-encoded epitranscriptomics was rejuvenated with the discovery of fat mass and obesity-associated protein (FTO) as the first m(6)A demethyl...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496078/ https://www.ncbi.nlm.nih.gov/pubmed/34704042 http://dx.doi.org/10.1039/d1cb00075f |