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Targeting the RNA demethylase FTO for cancer therapy

N (6)-Methyladenosine (m(6)A) is the most prevalent internal modification on mRNA and represents a new layer of gene expression in eukaryotes. The field of m(6)A-encoded epitranscriptomics was rejuvenated with the discovery of fat mass and obesity-associated protein (FTO) as the first m(6)A demethyl...

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Detalles Bibliográficos
Autores principales: Zhou, Lin-Lin, Xu, Hongjiao, Huang, Yue, Yang, Cai-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496078/
https://www.ncbi.nlm.nih.gov/pubmed/34704042
http://dx.doi.org/10.1039/d1cb00075f