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Genetic and epigenetic associations of ANRIL with coronary artery disease and risk factors

BACKGROUND: Both DNA genotype and methylation of antisense non-coding RNA in the INK4 locus (ANRIL) have been robustly associated with coronary artery disease (CAD), but the interdependent mechanisms of genotype and methylation remain unclear. METHODS: Eighteen tag single nucleotide polymorphisms (S...

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Detalles Bibliográficos
Autores principales: Xu, Bayi, Xu, Zhixia, Chen, Yequn, Lu, Nan, Shu, Zhouwu, Tan, Xuerui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496081/
https://www.ncbi.nlm.nih.gov/pubmed/34615528
http://dx.doi.org/10.1186/s12920-021-01094-8