Cargando…
Modelling hypersensitivity to trastuzumab defines biomarkers of response in HER2 positive breast cancer
BACKGROUND: Trastuzumab-based therapies are the therapeutic option for HER2 positive (HER2+) breast cancer. HER2 amplification is the only biomarker validated for trastuzumab-based therapies. However, a proportion of tumors become refractory during treatment course. For this reason, the finding of n...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496101/ https://www.ncbi.nlm.nih.gov/pubmed/34620206 http://dx.doi.org/10.1186/s13046-021-02098-z |