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Differential regulation of mRNA fate by the human Ccr4-Not complex is driven by coding sequence composition and mRNA localization

BACKGROUND: Regulation of protein output at the level of translation allows for a rapid adaptation to dynamic changes to the cell’s requirements. This precise control of gene expression is achieved by complex and interlinked biochemical processes that modulate both the protein synthesis rate and sta...

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Detalles Bibliográficos
Autores principales: Gillen, Sarah L., Giacomelli, Chiara, Hodge, Kelly, Zanivan, Sara, Bushell, Martin, Wilczynska, Ania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496106/
https://www.ncbi.nlm.nih.gov/pubmed/34615539
http://dx.doi.org/10.1186/s13059-021-02494-w