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Network propagation-based prioritization of long tail genes in 17 cancer types

BACKGROUND: The diversity of genomic alterations in cancer poses challenges to fully understanding the etiologies of the disease. Recent interest in infrequent mutations, in genes that reside in the “long tail” of the mutational distribution, uncovered new genes with significant implications in canc...

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Detalles Bibliográficos
Autores principales: Mohsen, Hussein, Gunasekharan, Vignesh, Qing, Tao, Seay, Montrell, Surovtseva, Yulia, Negahban, Sahand, Szallasi, Zoltan, Pusztai, Lajos, Gerstein, Mark B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496153/
https://www.ncbi.nlm.nih.gov/pubmed/34620211
http://dx.doi.org/10.1186/s13059-021-02504-x