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Micropattern platform promotes extracellular matrix remodeling by human PSC‐derived cardiac fibroblasts and enhances contractility of co‐cultured cardiomyocytes

In native heart tissue, cardiac fibroblasts provide the structural framework of extracellular matrix (ECM) while also influencing the electrical and mechanical properties of cardiomyocytes. Recent advances in the field of stem cell differentiation have led to the availability of human pluripotent st...

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Detalles Bibliográficos
Autores principales: Napiwocki, B.N., Stempien, A., Lang, D., Kruepke, R.A., Kim, G., Zhang, J., Eckhardt, L.L., Glukhov, A.V., Kamp, T.J., Crone, W.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496154/
https://www.ncbi.nlm.nih.gov/pubmed/34617673
http://dx.doi.org/10.14814/phy2.15045