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Micropattern platform promotes extracellular matrix remodeling by human PSC‐derived cardiac fibroblasts and enhances contractility of co‐cultured cardiomyocytes
In native heart tissue, cardiac fibroblasts provide the structural framework of extracellular matrix (ECM) while also influencing the electrical and mechanical properties of cardiomyocytes. Recent advances in the field of stem cell differentiation have led to the availability of human pluripotent st...
Autores principales: | Napiwocki, B.N., Stempien, A., Lang, D., Kruepke, R.A., Kim, G., Zhang, J., Eckhardt, L.L., Glukhov, A.V., Kamp, T.J., Crone, W.C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496154/ https://www.ncbi.nlm.nih.gov/pubmed/34617673 http://dx.doi.org/10.14814/phy2.15045 |
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