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Interleukin-6 promotes microtubule stability in axons via Stat3 protein–protein interactions

The interleukin-6 (IL-6) family of cytokines and its downstream effector, STAT3, are important mediators of neuronal health, repair, and disease throughout the CNS, including the visual system. Here, we elucidate a transcription-independent mechanism for the neuropoietic activities of IL-6 related t...

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Detalles Bibliográficos
Autores principales: Wareham, Lauren K., Echevarria, Franklin D., Sousa, Jennifer L., Konlian, Danielle O., Dallas, Gabrielle, Formichella, Cathryn R., Sankaran, Priya, Goralski, Peter J., Gustafson, Jenna R., Sappington, Rebecca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496173/
https://www.ncbi.nlm.nih.gov/pubmed/34646984
http://dx.doi.org/10.1016/j.isci.2021.103141