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Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis

Control of mRNA stability and degradation is essential for appropriate gene expression, and its dysregulation causes various disorders, including cancer, neurodegenerative diseases, diabetes, and obesity. The 5′–3′ exoribonuclease XRN1 executes the last step of RNA decay, but its physiological impac...

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Detalles Bibliográficos
Autores principales: Takaoka, Shohei, Yanagiya, Akiko, Mohamed, Haytham Mohamed Aly, Higa, Rei, Abe, Takaya, Inoue, Ken-ichi, Takahashi, Akinori, Stoney, Patrick, Yamamoto, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496175/
https://www.ncbi.nlm.nih.gov/pubmed/34646989
http://dx.doi.org/10.1016/j.isci.2021.103151