Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas

Deconstructing tissue-specific effects of genes and variants on proliferation is critical to understanding cellular transformation and systematically selecting cancer therapeutics. This requires scalable methods for multiplexed genetic screens tracking fitness across time, across lineages, and in a...

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Detalles Bibliográficos
Autores principales: Parekh, Udit, McDonald, Daniella, Dailamy, Amir, Wu, Yan, Cordes, Thekla, Zhang, Kun, Tipps, Ann, Metallo, Christian, Mali, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496177/
https://www.ncbi.nlm.nih.gov/pubmed/34646987
http://dx.doi.org/10.1016/j.isci.2021.103149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496177/
https://www.ncbi.nlm.nih.gov/pubmed/34646987
http://dx.doi.org/10.1016/j.isci.2021.103149

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