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Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas
Deconstructing tissue-specific effects of genes and variants on proliferation is critical to understanding cellular transformation and systematically selecting cancer therapeutics. This requires scalable methods for multiplexed genetic screens tracking fitness across time, across lineages, and in a...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496177/ https://www.ncbi.nlm.nih.gov/pubmed/34646987 http://dx.doi.org/10.1016/j.isci.2021.103149 |