The Mitochondrial Ca(2+) uniporter is a central regulator of interorganellar Ca(2+) transfer and NFAT activation

Mitochondrial Ca(2+) uptake tailors the strength of stimulation of plasma membrane phospholipase C–coupled receptors to that of cellular bioenergetics. However, how Ca(2+) uptake by the mitochondrial Ca(2+) uniporter (MCU) shapes receptor-evoked interorganellar Ca(2+) signaling is unknown. Here, we...

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Detalles Bibliográficos
Autores principales: Yoast, Ryan E., Emrich, Scott M., Zhang, Xuexin, Xin, Ping, Arige, Vikas, Pathak, Trayambak, Benson, J. Cory, Johnson, Martin T., Abdelnaby, Ahmed Emam, Lakomski, Natalia, Hempel, Nadine, Han, Jung Min, Dupont, Geneviève, Yule, David I., Sneyd, James, Trebak, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496184/
https://www.ncbi.nlm.nih.gov/pubmed/34499925
http://dx.doi.org/10.1016/j.jbc.2021.101174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496184/
https://www.ncbi.nlm.nih.gov/pubmed/34499925
http://dx.doi.org/10.1016/j.jbc.2021.101174

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