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The Mitochondrial Ca(2+) uniporter is a central regulator of interorganellar Ca(2+) transfer and NFAT activation
Mitochondrial Ca(2+) uptake tailors the strength of stimulation of plasma membrane phospholipase C–coupled receptors to that of cellular bioenergetics. However, how Ca(2+) uptake by the mitochondrial Ca(2+) uniporter (MCU) shapes receptor-evoked interorganellar Ca(2+) signaling is unknown. Here, we...
Autores principales: | Yoast, Ryan E., Emrich, Scott M., Zhang, Xuexin, Xin, Ping, Arige, Vikas, Pathak, Trayambak, Benson, J. Cory, Johnson, Martin T., Abdelnaby, Ahmed Emam, Lakomski, Natalia, Hempel, Nadine, Han, Jung Min, Dupont, Geneviève, Yule, David I., Sneyd, James, Trebak, Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496184/ https://www.ncbi.nlm.nih.gov/pubmed/34499925 http://dx.doi.org/10.1016/j.jbc.2021.101174 |
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