Spinal Cord Injury Induces Permanent Reprogramming of Microglia into a Disease-Associated State Which Contributes to Functional Recovery

Microglia are resident myeloid cells of the CNS. Recently, single-cell RNA sequencing (scRNAseq) has enabled description of a disease-associated microglia (DAM) with a role in neurodegeneration and demyelination. In this study, we use scRNAseq to investigate the temporal dynamics of immune cells har...

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Detalles Bibliográficos
Autores principales: Hakim, Ramil, Zachariadis, Vasilios, Sankavaram, Sreenivasa Raghavan, Han, Jinming, Harris, Robert A., Brundin, Lou, Enge, Martin, Svensson, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496189/
https://www.ncbi.nlm.nih.gov/pubmed/34417326
http://dx.doi.org/10.1523/JNEUROSCI.0860-21.2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496189/
https://www.ncbi.nlm.nih.gov/pubmed/34417326
http://dx.doi.org/10.1523/JNEUROSCI.0860-21.2021

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