Engineering threshold-based selection systems

Using model organisms to identify novel therapeutic targets is frequently constrained by pre-existing genetic toolkits. To expedite positive selection for identification of novel downstream effectors, we engineered conditional expression of activated CED-10/Rac to disrupt Caenorhabditis elegans embr...

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Detalles Bibliográficos
Autores principales: Pedone, Katherine H, González-Pérez, Vanessa, Leopold, Luciana E, Rasmussen, Neal R, Der, Channing J, Cox, Adrienne D, Ahmed, Shawn, Reiner, David J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496214/
https://www.ncbi.nlm.nih.gov/pubmed/34544135
http://dx.doi.org/10.1093/g3journal/jkab234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496214/
https://www.ncbi.nlm.nih.gov/pubmed/34544135
http://dx.doi.org/10.1093/g3journal/jkab234

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