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A two-stage testing strategy for detecting genes×environment interactions in association studies

Identifying gene×environment (G×E) interactions, especially when rare variants are included in genome-wide association studies, is a major challenge in statistical genetics. However, the detection of G×E interactions is very important for understanding the etiology of complex diseases. Although curr...

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Detalles Bibliográficos
Autores principales: Zhou, Jiabin, Li, Shitao, Zhou, Ying, Sheng, Xiaona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496220/
https://www.ncbi.nlm.nih.gov/pubmed/34568910
http://dx.doi.org/10.1093/g3journal/jkab220