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Chemical rescue of mutant proteins in living Saccharomyces cerevisiae cells by naturally occurring small molecules

Intracellular proteins function in a complex milieu wherein small molecules influence protein folding and act as essential cofactors for enzymatic reactions. Thus protein function depends not only on amino acid sequence but also on the concentrations of such molecules, which are subject to wide vari...

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Detalles Bibliográficos
Autores principales: Hassell, Daniel S, Steingesser, Marc G, Denney, Ashley S, Johnson, Courtney R, McMurray, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496222/
https://www.ncbi.nlm.nih.gov/pubmed/34544143
http://dx.doi.org/10.1093/g3journal/jkab252