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AddTag, a two-step approach with supporting software package that facilitates CRISPR/Cas-mediated precision genome editing

CRISPR/Cas-induced genome editing is a powerful tool for genetic engineering, however, targeting constraints limit which loci are editable with this method. Since the length of a DNA sequence impacts the likelihood it overlaps a unique target site, precision editing of small genomic features with CR...

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Detalles Bibliográficos
Autores principales: Seher, Thaddeus D, Nguyen, Namkha, Ramos, Diana, Bapat, Priyanka, Nobile, Clarissa J, Sindi, Suzanne S, Hernday, Aaron D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496238/
https://www.ncbi.nlm.nih.gov/pubmed/34544122
http://dx.doi.org/10.1093/g3journal/jkab216