Effects of kinship correction on inflation of genetic interaction statistics in commonly used mouse populations

It is well understood that variation in relatedness among individuals, or kinship, can lead to false genetic associations. Multiple methods have been developed to adjust for kinship while maintaining power to detect true associations. However, relatively unstudied are the effects of kinship on genet...

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Detalles Bibliográficos
Autores principales: Tyler, Anna L, El Kassaby, Baha, Kolishovski, Georgi, Emerson, Jake, Wells, Ann E, Mahoney, J Matthew, Carter, Gregory W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496251/
https://www.ncbi.nlm.nih.gov/pubmed/33892506
http://dx.doi.org/10.1093/g3journal/jkab131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496251/
https://www.ncbi.nlm.nih.gov/pubmed/33892506
http://dx.doi.org/10.1093/g3journal/jkab131

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