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Effects of kinship correction on inflation of genetic interaction statistics in commonly used mouse populations
It is well understood that variation in relatedness among individuals, or kinship, can lead to false genetic associations. Multiple methods have been developed to adjust for kinship while maintaining power to detect true associations. However, relatively unstudied are the effects of kinship on genet...
Autores principales: | Tyler, Anna L, El Kassaby, Baha, Kolishovski, Georgi, Emerson, Jake, Wells, Ann E, Mahoney, J Matthew, Carter, Gregory W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496251/ https://www.ncbi.nlm.nih.gov/pubmed/33892506 http://dx.doi.org/10.1093/g3journal/jkab131 |
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